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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159204Generated: October 27, 2026

Cyclopropanemethanol → 5-(4-Fluorophenyl)-6-cyclopropylmethoxy-nicotinic acid

https://huagongshe.com/reaction/1159204

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanolHCID 75644—
Reactant6-Chloro-5-(4-fluoro-phenyl)-nicotinic acidHCID 46313827—
Product5-(4-Fluorophenyl)-6-cyclopropylmethoxy-nicotinic acidHCID 21109721—

Reaction Steps

The title compound was synthesized in analogy to Example 5c, using 6-chloro-5-(4-fluoro-phenyl)-nicotinic acid and (hydroxymethyl)cyclopropane as starting materials, MS (ISP) 286.0 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812028B2
Source datasetuspto-grants-2010_10
ORD IDord-a3c40af9bddf4f60ad24f5b8970d837f
Source noteuspto-grants-2010_10