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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159247Generated: November 1, 2026

4-Chlorophenylboronic acid → HCID 67505405, compound

https://huagongshe.com/reaction/1159247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
SolventIsopropanolHCID 3776—
ProductHCID 67505405HCID 67505405—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, 4-chlorophenyl-boronic acid (commercially available), isopropanol (commercially available), and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (ISP): 389.3, 391.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812028B2
Source datasetuspto-grants-2010_10
ORD IDord-b863353d2f214ad5bbf5529564ccf839
Source noteuspto-grants-2010_10