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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159265Generated: November 1, 2026

N-Methylpropylamine → HCID 11950230, compound

https://huagongshe.com/reaction/1159265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylpropylamineHCID 12315—
Reactant4-Chlorophenylboronic acidHCID 74299—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ReactantCyclohexanol, 2-amino-, hydrochloride (1:1), (1R,2R)-HCID 12228412—
ProductHCID 11950230HCID 11950230—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, N-methyl-N-propylamine, (4-chloro-phenyl)-boronic acid and (1R,2R)-2-amino-cyclohexanol hydrochloride as starting materials. MS (ISP): 402.3 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812028B2
Source datasetuspto-grants-2010_10
ORD IDord-d28cc746108f46b1ba2e483310d8f886
Source noteuspto-grants-2010_10