HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminocyclopentanemethanol → HCID 67505156, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminocyclopentanemethanol | HCID 66307 | — |
| Reactant | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | 1-(Hydroxymethyl)cyclopropan-1-ol | HCID 15887890 | — |
| Product | HCID 67505156 | HCID 67505156 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 31, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, hydroxymethylcyclopropanol, (4-fluoro-phenyl)-boronic acid and 1-amino-cyclopentanemethanol as starting materials to yield 6-cyclopropylmethoxy-5-(4-fluoro-phenyl)-N-(1-hydroxymethyl-cyclopentyl)-nicotinamide as a colorless foam, MS (ISP) 385.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812028B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-f5136357580d40e394e8b73eaa5d4f70 |
| Source note | uspto-grants-2010_10 |