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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159345Generated: October 31, 2026

Pyrrolidine → HCID 24857074, compound

https://huagongshe.com/reaction/1159345

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantD(-)-LeucinolHCID 2724002—
Reactant(3-Chlorophenyl)boronic acidHCID 2734323—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 24857074HCID 24857074—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 43, using 5-bromo-6-chloro-nicotinic acid methyl ester, pyrrolidine (commercially available), 3-chlorophenyl-boronic acid (commercially available) and (R)-(−)-leucinol (commercially available) as starting materials. MS (ISP): 402.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812028B2
Source datasetuspto-grants-2010_10
ORD IDord-33c09e2dfdb4425792f49696e8e33c0d
Source noteuspto-grants-2010_10