HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-5-methylphenyl isocyanate → HCID 11603505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-5-methylphenyl isocyanate | HCID 2733377 | — |
| Reactant | 4-(4-Amino-phenyl)-1-methyl-1H-pyrazolo[3,4-c]pyridin-3-ylamine | HCID 68644474 | — |
| Reactant | HCID 86606989 | HCID 86606989 | — |
| Product | HCID 11603505 | HCID 11603505 | — |
Reaction Steps
The title compound was prepared using the procedure described in Example 1E using the product from Example 6A and 1-fluoro-4-isocyanato-4-methyl-benzene instead of the product from Example 1D and 1-fluoro-2-isocyanato-4-methyl-benzene. MS (ESI(+)) m/e 391 (M+H)+; 1H NMR (300 MHz, DMSO-D6) δ ppm 2.22 (d, J=1.70 Hz, 3H) 4.02 (s, 3H) 7.06 (t, J=9.15 Hz, 1H) 7.24-7.33 (m, 1H) 7.35-7.43 (m, 1H) 7.52 (d, J=8.81 Hz, 2H) 7.67 (d, J=8.81 Hz, 2H) 8.10 (s, 1H) 8.77 (s, 1H) 8.99 (s, 1H) 9.21 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812166B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-403700a6de234fa0b9da228e565e8404 |
| Source note | uspto-grants-2010_10 |