HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-5-methylphenyl isocyanate → HCID 11683719, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-5-methylphenyl isocyanate | HCID 2733377 | — |
| Reactant | 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate | HCID 2733380 | — |
| Reactant | 4-(4-Amino-phenyl)-1-methyl-1H-pyrazolo[3,4-c]pyridin-3-ylamine | HCID 68644474 | — |
| Product | HCID 11683719 | HCID 11683719 | — |
Reaction Steps
The title compound was prepared using the procedure described in Example 1E using the product from Example 6A and 1-fluoro-2-isocyanato-4-trifluoromethyl-benzene instead of the product from Example 1D and 1-fluoro-2-isocyanato-4-methyl-benzene. MS (ESI(+)) m/e 445 (M+H)+; 1H NMR (500 MHz, DMSO-D6) δ ppm 3.92 (s, 3H) 4.66 (s, 2H) 7.36-7.45 (m, 1H) 7.46-7.55 (m, 1H) 7.50 (d, J=8.73 Hz, 2H) 7.65 (d, J=8.42 Hz, 2H) 7.95 (s, 1H) 8.64 (dd, J=7.33, 2.03 Hz, 1H) 8.87 (s, 1H) 8.95 (d, J=2.81 Hz, 1H) 9.35 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812166B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-2027be6114d1489a9964a3e9279282a7 |
| Source note | uspto-grants-2010_10 |