HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22931050, compound → HCID 58863436, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22931050 | HCID 22931050 | — |
| Reactant | HCID 58863437 | HCID 58863437 | — |
| Product | HCID 58863436 | HCID 58863436 | 26% |
Reaction Steps
In the same manner as in Example 16b and using N,N-diethyl-3-fluoro-2-methylbenzamide (3.46 g) and (R)-3-(3-hydroxypyrrolidin-1-yl)-N-methoxy-N-methylpropanamide (3.36 g), (R)-5-fluoro-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-2H-isoquinolin-1-one (1.19 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812178B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-882fc597fb114be6a57e66139fefeb5f |
| Source note | uspto-grants-2010_10 |