HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-3,4-epoxy-6-cyanochroman → 4-(2-Amino-quinolin-4-yloxy)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-3,4-epoxy-6-cyanochroman | HCID 10867360 | — |
| Reactant | HCID 178507928 | HCID 178507928 | — |
| Product | 4-(2-Amino-quinolin-4-yloxy)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile | HCID 16040659 | — |
Reaction Steps
Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 2-amino-quinolin-4-ol as starting materials, the title compound was prepared as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812183B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-e8e5da45147e4826862ad59ba1966349 |
| Source note | uspto-grants-2010_10 |