2-Phenylimidazole → HCID 16048737, compound

HRID 1159600Notes

Reaction equation

HRID 1159600 reaction equation
[CH3:1][C:2]1([CH3:15])[O:11][C:10]2[C:5](=[CH:6][C:7]([C:12]#[N:13])=[CH:8][CH:9]=2)[CH:4]2O[CH:3]12.[C:16]1([C:22]2[NH:23][CH:24]=[CH:25][N:26]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:1][C:2]1([CH3:15])[CH:3]=[C:4]([N:23]2[CH:24]=[CH:25][N:26]=[C:22]2[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:5]2[C:10](=[CH:9][CH:8]=[C:7]([C:12]#[N:13])[CH:6]=2)[O:11]1

Participants

3

Reactant 2

HCID 695912-PhenylimidazoleHCID 108673602,2-Dimethyl-3,4-epoxy-6-cyanochroman

Product 1

HCID 16048737HCID 16048737, compound

Procedure

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 2-phenyl-1H-imidazole as starting materials, the title compounds were prepared as white solids.

Sources & evidence

ORD record
ord-c82ca5095eaa441a8eba1ecc045b89f5
Source dataset
uspto-grants-2010_10
Patent number
US07812183B2

Reaction notes

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