2,2-Dimethyl-3,4-epoxy-6-cyanochroman → HCID 66700135, compound

HRID 1159601Notes

Reaction equation

HRID 1159601 reaction equation
[CH3:1][C:2]1([CH3:15])[O:11][C:10]2[C:5](=[CH:6][C:7]([C:12]#[N:13])=[CH:8][CH:9]=2)[CH:4]2[O:14][CH:3]12.[CH3:16][C:17]1[N:18]=[C:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[NH:20][CH:21]=1>>[OH:14][CH:3]1[CH:4]([N:20]2[CH:21]=[C:17]([CH3:16])[N:18]=[C:19]2[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[C:5]2[C:10](=[CH:9][CH:8]=[C:7]([C:12]#[N:13])[CH:6]=2)[O:11][C:2]1([CH3:15])[CH3:1]

Participants

3

Reactant 2

HCID 108673602,2-Dimethyl-3,4-epoxy-6-cyanochromanHCID 178430841HCID 178430841, compound

Product 1

HCID 66700135HCID 66700135, compound

Procedure

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 4-methyl-2-phenyl-1H-imidazole as starting materials, the title compound was prepared as a white solid.

Sources & evidence

ORD record
ord-afb49895cfe3430d9db311b6e12f0204
Source dataset
uspto-grants-2010_10
Patent number
US07812183B2

Reaction notes

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