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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159603Generated: November 3, 2026

4-(4-Chlorophenyl)Imidazole → 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-2H-chromene-6-carbonitrile

https://huagongshe.com/reaction/1159603

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorophenyl)ImidazoleHCID 448632—
Reactant2,2-Dimethyl-3,4-epoxy-6-cyanochromanHCID 10867360—
Product4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-2H-chromene-6-carbonitrileHCID 16048739—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 5-(4-chloro-phenyl)-1H-imidazole as starting materials, the title compounds were prepared as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812183B2
Source datasetuspto-grants-2010_10
ORD IDord-ec4f2f068366487ea21696ed1b5501fc
Source noteuspto-grants-2010_10