1-(4-Nitrophenyl)piperazine → HCID 66699847, compound

HRID 1159607Notes

Reaction equation

HRID 1159607 reaction equation
[CH3:1][C:2]1([CH3:15])[O:11][C:10]2[C:5](=[CH:6][C:7]([C:12]#[N:13])=[CH:8][CH:9]=2)[CH:4]2[O:14][CH:3]12.[N+:16]([C:19]1[CH:24]=[CH:23][C:22]([N:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:21][CH:20]=1)([O-:18])=[O:17]>>[OH:14][CH:3]1[CH:4]([N:28]2[CH2:29][CH2:30][N:25]([C:22]3[CH:21]=[CH:20][C:19]([N+:16]([O-:18])=[O:17])=[CH:24][CH:23]=3)[CH2:26][CH2:27]2)[C:5]2[C:10](=[CH:9][CH:8]=[C:7]([C:12]#[N:13])[CH:6]=2)[O:11][C:2]1([CH3:15])[CH3:1]

Participants

3

Reactant 2

HCID 804471-(4-Nitrophenyl)piperazineHCID 108673602,2-Dimethyl-3,4-epoxy-6-cyanochroman

Product 1

HCID 66699847HCID 66699847, compound

Procedure

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 1-(4-nitro-phenyl)-piperazine as starting material, the title compound was prepared as a white solid.

Sources & evidence

ORD record
ord-fda5ef8bc2414773ba945450abe29c6e
Source dataset
uspto-grants-2010_10
Patent number
US07812183B2

Reaction notes

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