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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159614Generated: October 27, 2026

5-Chloro-2-benzothiazolamine → 4-(5-Chloro-benzothiazol-2-ylamino)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile

https://huagongshe.com/reaction/1159614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-benzothiazolamineHCID 30120—
Reactant2,2-Dimethyl-3,4-epoxy-6-cyanochromanHCID 10867360—
Product4-(5-Chloro-benzothiazol-2-ylamino)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrileHCID 86611017—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 5-chloro-benzothiazol-2-ylamine as starting material, the title compound was prepared as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812183B2
Source datasetuspto-grants-2010_10
ORD IDord-3962dafec893475397630288a7a7a58f
Source noteuspto-grants-2010_10