HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxy-1,2-benzisoxazole → (3S,4R)-4-(Benzo[d]isoxazol-3-yloxy)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxy-1,2-benzisoxazole | HCID 210830 | — |
| Reactant | (1aS,7bS)-2,2-Dimethyl-1a,7b-dihydro-2H-oxireno[2,3-c]chromene-6-carbonitrile | HCID 9837089 | — |
| Product | (3S,4R)-4-(Benzo[d]isoxazol-3-yloxy)-3-hydroxy-2,2-dimethyl-chroman-6-carbonitrile | HCID 68644303 | — |
Reaction Steps
Following the procedure in Example 1, using (S,S)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and benzo[d]isoxazol-3-one as starting materials, the title compound was prepared as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812183B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-6ddcac7bc7f24b529d1b75e1623b2232 |
| Source note | uspto-grants-2010_10 |