HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)Imidazole → 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)Imidazole | HCID 448632 | — |
| Reactant | 3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine | HCID 10856030 | — |
| Product | 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-ol | HCID 66700102 | — |
Reaction Steps
Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-6-aza-cyclopropa[a]naphthalene (literature known compound) and 5-(4-chloro-phenyl)-1H-imidazole as starting materials, the title compound was prepare das a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812183B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-3ee72e698efb4926999b752accb11860 |
| Source note | uspto-grants-2010_10 |