2-(4-chlorophenyl)-1H-imidazole → 4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-ol

Participants

Role	Name	HCID	Charge
Reactant	2-(4-chlorophenyl)-1H-imidazole	HCID 242948	—
Reactant	3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine	HCID 10856030	—
Product	4-[2-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-ol	HCID 66699841	—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-6-aza-cyclopropa[a]naphthalene and 2-(4-chloro-phenyl)-1H-imidazole as starting materials, the title compound was prepared as a pale yellow solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07812183B2
Source dataset	uspto-grants-2010_10
ORD ID	ord-098dd75d2825452a877de6d9bcf35fd4
Source note	uspto-grants-2010_10