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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159632Generated: October 30, 2026

3-(4-chlorophenyl)-1H-pyrazole → 4-[5-(4-Chloro-phenyl)-pyrazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-ol

https://huagongshe.com/reaction/1159632

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-chlorophenyl)-1H-pyrazoleHCID 714291—
Reactant3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridineHCID 10856030—
Product4-[5-(4-Chloro-phenyl)-pyrazol-1-yl]-2,2-dimethyl-3,4-dihydro-2H-pyrano[3,2-c]pyridin-3-olHCID 66700057—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-6-aza-cyclopropa[a]naphthalene and 5-(4-chloro-phenyl)-1H-pyrazole as starting materials, the title compound was prepared as a pale yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812183B2
Source datasetuspto-grants-2010_10
ORD IDord-31ce1864523f41e3b79c83b0f82c7649
Source noteuspto-grants-2010_10