3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridine → HCID 66700075, compound

HRID 1159635Notes

Reaction equation

HRID 1159635 reaction equation
[CH3:1][C:2]1([CH3:13])[O:11][C:10]2[C:5](=[CH:6][N:7]=[CH:8][CH:9]=2)[CH:4]2[O:12][CH:3]12.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH:25]=[CH:24][C:23](=[O:26])[NH:22]2)=[CH:17][CH:16]=1>>[Cl:14][C:15]1[CH:16]=[CH:17][C:18]([N:21]2[CH:25]=[CH:24][C:23]([O:26][CH:4]3[C:5]4[CH:6]=[N:7][CH:8]=[CH:9][C:10]=4[O:11][C:2]([CH3:1])([CH3:13])[CH:3]3[OH:12])=[N:22]2)=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 108560303,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-pyrano[3,2-c]pyridineHCID 113560261-(4-Chlorophenyl)-1,2-dihydro-3H-pyrazol-3-one

Product 1

HCID 66700075HCID 66700075, compound

Procedure

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-6-aza-cyclopropa[a]naphthalene and 1-(4-chloro-phenyl)-1,2-dihydro-pyrazol-3-one as starting materials, the title compounds were prepared as pale yellow solids.

Sources & evidence

ORD record
ord-02e1c92ef87248f38d9b82c3463ae798
Source dataset
uspto-grants-2010_10
Patent number
US07812183B2

Reaction notes

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