2,6-Lutidine → HCID 86618238, compound

Participants

Reaction Steps

The experimental for Intermediate 16 was followed using 1-(2-thienylsulfonyl)-4-vinyl-1H-indole (333 mg, 1.15 mmol; Intermediate 21), OsO4 (15 mg, 0.06 mmol), 2,6-lutidine (268 μL, 2.30 mmol) and sodium periodate (0.984 g, 4.60 mmol). The title compound was obtained (306 mg, 91%, still some dioxane according to HNMR) as a black gum. MS (ESI+) for C13H9NO3S2 m/z 292 (M+H)+.

Provenance & Evidence