HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-4-carbonyl chloride → HCID 59513876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-4-carbonyl chloride | HCID 2800003 | — |
| Reactant | 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-fluorophenyl)-2-pyrimidinamine | HCID 59511403 | — |
| Reactant | N-(3-{3-[2-(1,2,3,4-tetrahydro-7-isoquinolinylamino)-4-pyrimidinyl]-pyrazolo[1,5-a]pyridin-2-yl}phenyl)benzamide | HCID 59513880 | — |
| Product | HCID 59513876 | HCID 59513876 | — |
Reaction Steps
In a manner analogous to Example 66, 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-fluorophenyl)-2-pyrimidinamine and 2-chloro-4-pyridinecarbonyl chloride are used to prepare the title compound. HRMS calcd for C29H19ClFN7O: 535.1324, found: 536.1392 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812022B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-c2e2d3ec0a974d09a09244176262ba09 |
| Source note | uspto-grants-2010_10 |