反应详情

The title compound was prepared from N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2,6-difluorobenzamide and N-(4-aminophenyl)-N2,N2-dimethylglycinamide by a procedure similar to Example 64. 1H NMR (400 MHz, DMSO-d6) δ 2.29 (s, 6H), 3.09 (s, 2H), 6.46 (d, 1H, J=5.3 Hz), 7.10 (t, 1H, J=6.7 Hz), 7.22 (d, 2H, J=8.0 Hz), 7.34 (d, 1H, J=7.7 Hz), 7.42-7.51 (m, 4H), 7.56 (t, 1H, J=8.2 Hz), 7.61 (d, 2H, J=8.9 Hz), 7.80 (d, 1H, J=8.0 Hz), 7.96 (s, 1H), 8.22 (d, 1H, J=5.3 Hz), 8.46 (bd, 1H, J=8.8 Hz), 8.82 (d, 1H, J=6.8 Hz), 9.47 (s, 1H), 9.60 (s, 1H), 10.91 (s, 1H); ESIMS (M+H)+=619.