HRID1159927

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79278

5-Ethylsulphonyl-o-anisidine

C9H13NO3S

反应SMILES：O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F

HCID59513803

未命名化合物

PRODUCTS

产物

反应SMILES：O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Nc3ccc4c(c3)CNCC4)n2)c1)c1ccccc1

HCID59513880

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a procedure similar to Example 27, Step D using N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2,6-difluorobenzamide and [5-(ethylsulfonyl)-2-(methyloxy)phenyl]amine: MS (APCI): 641 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-87a7036e4f9a42eebe4aec74dcfbc94f
来源数据集: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07812022B2
来源说明: uspto-grants-2010_10

反应SMILES

Cl[C:2]1[N:7]=[C:6]([C:8]2[C:9]([C:17]3[CH:18]=[C:19]([NH:23][C:24](=[O:33])[C:25]4[C:30](F)=[CH:29][CH:28]=[CH:27][C:26]=4F)[CH:20]=[CH:21][CH:22]=3)=[N:10][N:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=23)[CH:5]=[CH:4][N:3]=1.C(S([C:39]1[CH:40]=[CH:41][C:42](OC)=[C:43]([NH2:45])[CH:44]=1)(=O)=O)C>>[CH2:2]1[C:39]2[C:40](=[CH:41][CH:42]=[C:43]([NH:45][C:2]3[N:7]=[C:6]([C:8]4[C:9]([C:17]5[CH:18]=[C:19]([NH:23][C:24](=[O:33])[C:25]6[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=6)[CH:20]=[CH:21][CH:22]=5)=[N:10][N:11]5[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=45)[CH:5]=[CH:4][N:3]=3)[CH:44]=2)[CH2:5][CH2:4][NH:3]1