Nitric Acid → HCID 68644119, compound

Participants

Reaction Steps

Cyanamide (1.3 mL, 16.8 mmol, 50% by wt. in water), 3-fluoroaniline (1.34 mL, 14 mmol), and 14 M nitric acid (1 mL, 14 mmol) were refluxed in EtOH (14 mL) for 15 h. The reaction was cooled and poured into diethylether. The resulting white suspension was filtered and dried under vacuum. Yield: 1.17 g (38%) of a white powder. 1H NMR (400 MHz, DMSO-d6) δ 9.65 (brs, 1H), 7.43 (m, 5H), 7.16-6.90 (m, 3H).

Provenance & Evidence