Dimethylamine → HCID 59511423, compound

HRID 1160011Notes

Reaction equation

HRID 1160011 reaction equation
FC1C=CC(F)=CC=1C([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([C:13]2[C:21]([C:22]3[CH:27]=[CH:26][N:25]=[C:24]([NH:28][C:29]4[CH:34]=[CH:33][CH:32]=[C:31]([O:35][CH2:36]CN(C)CC=C)[CH:30]=4)[N:23]=3)=[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][N:15]3[N:14]=2)[CH:8]=1)=O.ClCCCOC1C=C(NC2N=C(C3C(C4C=[C:77]([NH:81][C:82](=O)[C:83](F)(F)F)C=CC=4)=NN4C=CC=CC=34)C=CN=2)C=CC=1.[CH3:88]NC>>[NH2:6][C:7]1[CH:8]=[C:9]([C:13]2[C:21]([C:22]3[CH:27]=[CH:26][N:25]=[C:24]([NH:28][C:29]4[CH:34]=[CH:33][CH:32]=[C:31]([O:35][CH2:36][CH2:83][CH2:82][N:81]([CH3:88])[CH3:77])[CH:30]=4)[N:23]=3)=[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][N:15]3[N:14]=2)[CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 11671800HCID 11671800, compoundHCID 59511411HCID 59511411, compound

Product 1

HCID 59511423HCID 59511423, compound

Procedure

The title compound may be prepared by treating N-(3-{3-[2-({3-[(3-chloropropyl)oxy]phenyl}amino)-4-pyrimidinyl]pyrazolo[1,5-a]pyridin-2-yl}phenyl)-2,2,2-trifluoroacetamide with dimethylamine to give product.

Workup

  1. customto give product

Sources & evidence

ORD record
ord-fe0ed2aa869248019c85edc4f65f55f9
Source dataset
uspto-grants-2010_10
Patent number
US07812022B2

Reaction notes

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