Piperidine → HCID 131726440, compound

Participants

Reaction Steps

In a round bottom flask (25 mL), Fmoc-Met-Ala-Leu-OBn (SEQ. ID NO: 3) is dissolved in 5 mL of anhydrous DMF. Piperidine is added to the solution and the mixture is stirred at room temperature for 25 minutes. The reaction is quenched with water and extracted with ethyl acetate. The combined organic layer is further washed by water, brine and dried over sodium sulfate. Solid Met-Ala-Leu-OBn (SEQ ID NO: 3) is obtained after removal of solvent.

Provenance & Evidence