HCID 12158081, compound → HCID 86613474, compound

HRID 1160196Notes

Reaction equation

HRID 1160196 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11](Br)=[CH:10][CH:9]=2)[O:5][C:6]=1[CH3:7].C[Sn](C)(C)[C:17]1[CH:22]=[CH:21][C:20]([N:23]2[CH2:27][C@H:26]([CH2:28][C:29](=[O:33])[C:30]([NH2:32])=[O:31])[O:25][CH2:24]2)=[CH:19][C:18]=1[F:34]>>[CH3:1][C:2]1[N:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([C:17]3[CH:22]=[CH:21][C:20]([N:23]4[CH2:27][C@H:26]([CH2:28][C:29](=[O:33])[C:30]([NH2:32])=[O:31])[O:25][CH2:24]4)=[CH:19][C:18]=3[F:34])=[CH:10][CH:9]=2)[O:5][C:6]=1[CH3:7]

Participants

3

Reactant 2

HCID 12158081HCID 12158081, compoundHCID 86613473HCID 86613473, compound

Product 1

HCID 86613474HCID 86613474, compound

Procedure

The same procedure as in Example 1 was conducted, except for adding 4-(4,5-dimethyloxazol-2-yl)-bromobenzene and using (S)-3-(4-trimethylstannyl-3-fluorophenyl)-2-oxo-5-oxazolidinylmethyl acetamide as a starting material, to obtain the title compound.

Sources & evidence

ORD record
ord-5b9cc3e493e0479987c93b2e515a35c1
Source dataset
uspto-grants-2010_10
Patent number
US07816379B2

Reaction notes

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