HCID 67075008, compound → HCID 86613476, compound

HRID 1160198Notes

Reaction equation

HRID 1160198 reaction equation
[OH:1][CH2:2][C@H:3]1[CH2:7][O:6][C:5]([C:8]2[CH:13]=[CH:12][C:11](Br)=[CH:10][CH:9]=2)=[N:4]1.C[Sn](C)(C)[C:17]1[CH:22]=[CH:21][C:20]([N:23]2[CH2:27][C@H:26]([CH2:28][C:29](=[O:33])[C:30]([NH2:32])=[O:31])[O:25][CH2:24]2)=[CH:19][C:18]=1[F:34]>>[OH:1][CH2:2][C@H:3]1[CH2:7][O:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:17]3[CH:22]=[CH:21][C:20]([N:23]4[CH2:27][C@H:26]([CH2:28][C:29](=[O:33])[C:30]([NH2:32])=[O:31])[O:25][CH2:24]4)=[CH:19][C:18]=3[F:34])=[CH:10][CH:9]=2)=[N:4]1

Participants

3

Reactant 2

HCID 67075008HCID 67075008, compoundHCID 86613473HCID 86613473, compound

Product 1

HCID 86613476HCID 86613476, compound

Procedure

The same procedure as in Example 1 was conducted, except for adding 4-(4(S)-hydroxymethyl-4,5-dihydrooxazol-2-yl)-bromobenzene and using (S)-3-(4-trimethylstannyl-3-fluorophenyl)-2-oxo-5-oxazolidinylmethyl acetamide as a starting material, to obtain the title compound.

Sources & evidence

ORD record
ord-60ad9e0c9e144d8bb65019147d65fed7
Source dataset
uspto-grants-2010_10
Patent number
US07816379B2

Reaction notes

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