HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-2-carboxylic acid → 3-(Indole-2-carbonylamino)-3,4-dihydrocarbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-2-carboxylic acid | HCID 72899 | — |
| Reactant | 3-Amino-3,4-dihydroquinolin-2(1H)-one--hydrogen chloride (1/1) | HCID 13499428 | — |
| Product | 3-(Indole-2-carbonylamino)-3,4-dihydrocarbostyril | HCID 11779854 | — |
Reaction Steps
The title compound was prepared by the methods of Example 5 using 3-amino-3,4-dihydrocarbostyril hydrochloride in place of (R)-3-amino-3,4-dihydrocarbostyril hydrochloride and indole-2-carboxylic acid in place of 5-chloroindole-2-carboxylic acid. HPLC/MS [M+H]+, 306; [M+Na]+, 328.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07098235B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-5b68b01f24c048a9abcf80baf3ff1997 |
| Source note | uspto-grants-2006_08 |