HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxypyridine → HCID 21901945, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxypyridine | HCID 7971 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Methanesulfonic acid 1-[1-(4-chloro-phenyl)-cyclobutanecarbonyl]-piperidin-3-ylmethyl ester | HCID 12992442 | — |
| Reactant | HCID 21902076 | HCID 21902076 | — |
| Product | HCID 21901945 | HCID 21901945 | 52% |
Reaction Steps
Compound 85 was synthesized from 3-hydroxypyridine (0.25 g, 2.60 mmol), cesium carbonate (1.27 g, 3.89 mmol) and compound 43 (1.0 g, 2.60 mmol), using the method described for the synthesis of compound 44 to give 0.52 g of the desired product 85. C22H25ClN2O2, LRMS (m/z)=385 MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816375B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-2f163ae9e7374e0c996eca0a838678c6 |
| Source note | uspto-grants-2010_10 |