HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1160741Generated: October 30, 2026
Ethyl chloroformate → HCID 24830152, compound
https://huagongshe.com/reaction/1160741
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | HCID 24830151 | HCID 24830151 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 24830152 | HCID 24830152 | 97% |
Reaction Steps
Compound 11 (31 mg, 0.074 mmol) was dissolved in methylene chloride (2 mL) at room temperature. Ethyl chloroformate (14 ul, 2 eq) was added to the solution and it was heated to 110° C. in the microwave for 1 hour. The solvent was removed and the crude mixture was flashed with ethyl acetate/hexane to produce 28.4 mg (97% yield) of Compound 12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07816535B2 |
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| Source dataset | uspto-grants-2010_10 |
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| ORD ID | ord-01059a20a3ad4791aa406aec38a2871f |
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| Source note | uspto-grants-2010_10 |
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