Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1160813Generated: October 28, 2026

HCID 66995060, compound → Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate

https://huagongshe.com/reaction/1160813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66995060HCID 66995060—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductEthyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylateHCID 135627703—

Reaction Steps

Ethyl 2-[4-(benzyloxy)-3-cyanophenyl]-4-methyl-1,3-thiazole-5-carboxylate was suspended in a mixture of THF and ethanol, then palladium-carbon was added thereto, and the mixture was stirred under a hydrogen atmosphere at room temperature to obtain ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate. APN: 287.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07816558B2
Source datasetuspto-grants-2010_10
ORD IDord-1542e8e4136a46b3a921eeb416a51eed
Source noteuspto-grants-2010_10