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HRID1160814

反应详情

EQUATION

反应方程式

HRID 1160814 的结构方程式

REACTANTS

反应物

3
结构：[Cs+].[F-]
HCID25953

Cesium fluoride

CsF

结构：COC(=O)c1ccnc(Cl)c1
HCID2736842

Methyl 2-chloroisonicotinate

C7H6ClNO2

结构：N#Cc1cc(OB(O)O)ccc1F
HCID67078661

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccnc(-c2ccc(F)c(C#N)c2)c1
HCID66995083

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
催化剂HCID178418397

未命名化合物

结构：COCCOC
溶剂HCID8071

未命名化合物

PROCEDURE

实验过程

Cesium fluoride and tetrakis(triphenylphosphine)palladium were added to a 1,2-dimethoxyethane solution of (3-cyano-4-fluorophenyl)boric acid and methyl 2-chloroisonicotinate, and the mixture was heated under reflux in an argon atmosphere to obtain methyl 2-(3-cyano-4-fluorophenyl)isonicotinate. F: 257.

WORKUP

后处理

  1. temperaturethe mixture was heated
  2. temperatureunder reflux in an argon atmosphere