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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1160909Generated: October 30, 2026

4-Chlorophenylboronic acid → 3-{4-[1-(4'-Chloro-biphenyl-4-yloxy)-heptyl]-benzoylamino}-propionic acid

https://huagongshe.com/reaction/1160909

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant3-{4-[1-(4-Bromo-phenoxy)-heptyl]-benzoylamino}-propionic acid methyl esterHCID 67153387—
Product3-{4-[1-(4'-Chloro-biphenyl-4-yloxy)-heptyl]-benzoylamino}-propionic acidHCID 59518036—

Reaction Steps

This compound is made in a substantially similar manner to Example 117 using isomer 1 of 3-{4-[1-(4-bromo-phenoxy)-heptyl]-benzoylamino}-propionic acid methyl ester and 4-chlorophenylboronic acid as starting materials in step D. MS (ES): 492.3 [M−H]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07816557B2
Source datasetuspto-grants-2010_10
ORD IDord-fcda193a5eb143789256e87e28c9606f
Source noteuspto-grants-2010_10