4-tert-Butylphenylboronic acid → HCID 59518145, compound

HRID 1160940Notes

Reaction equation

HRID 1160940 reaction equation
C[O:2][C:3](=[O:33])[CH2:4][CH2:5][NH:6][C:7](=[O:32])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([S:22][C:23]2[CH:28]=[C:27]([CH3:29])[C:26](Br)=[C:25]([CH3:31])[CH:24]=2)[CH2:15][CH2:16][CH2:17][C:18]([F:21])([F:20])[F:19])=[CH:10][CH:9]=1.[C:34]([C:38]1[CH:43]=[CH:42][C:41](B(O)O)=[CH:40][CH:39]=1)([CH3:37])([CH3:36])[CH3:35]>>[C:34]([C:38]1[CH:43]=[CH:42][C:41]([C:26]2[C:27]([CH3:29])=[CH:28][C:23]([S:22][CH:14]([C:11]3[CH:10]=[CH:9][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:33])=[O:32])=[CH:13][CH:12]=3)[CH2:15][CH2:16][CH2:17][C:18]([F:20])([F:21])[F:19])=[CH:24][C:25]=2[CH3:31])=[CH:40][CH:39]=1)([CH3:37])([CH3:36])[CH3:35]

Participants

3

Reactant 2

HCID 27343204-tert-Butylphenylboronic acidHCID 67153472HCID 67153472, compound

Product 1

HCID 59518145HCID 59518145, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 358 starting from 3-{4-[1-(4-bromo-3,5-dimethyl-phenylsulfanyl)-5,5,5-trifluoro-pentyl]-benzoylamino}-propionic acid methyl ester and 4-tert-butyl phenyl boronic acid. MS: 584.2 [M−H]−.

Sources & evidence

ORD record
ord-d2ab3ae080c245e9ac54101e5f86d732
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

Loading…