HCID 59518096, compound → HCID 59518108, compound

HRID 1160941Notes

Reaction equation

HRID 1160941 reaction equation
C[O:2][C:3](=[O:23])[CH2:4][CH2:5][NH:6][C:7](=[O:22])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([OH:21])[CH2:15][CH2:16][C:17]([F:20])([F:19])[F:18])=[CH:10][CH:9]=1.[CH3:24][C:25]1[CH:26]=[C:27](O)[CH:28]=[N:29][C:30]=1[C:31]1[CH:36]=[CH:35][C:34]([C:37]([F:40])([F:39])[F:38])=[CH:33][CH:32]=1>>[F:18][C:17]([F:20])([F:19])[CH2:16][CH2:15][CH:14]([C:11]1[CH:12]=[CH:13][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:23])=[O:22])=[CH:9][CH:10]=1)[O:21][C:27]1[CH:28]=[N:29][C:30]([C:31]2[CH:36]=[CH:35][C:34]([C:37]([F:39])([F:40])[F:38])=[CH:33][CH:32]=2)=[C:25]([CH3:24])[CH:26]=1

Participants

3

Reactant 2

HCID 59518096HCID 59518096, compoundHCID 59518112HCID 59518112, compound

Product 1

HCID 59518108HCID 59518108, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 1 starting from 3-[4-(4,4,4-trifluoro-1-hydroxy-butyl)-benzoylamino]-propionic acid methyl ester and 5-methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ol (Preparation 34). MS: 553.3 [M−H]−.

Sources & evidence

ORD record
ord-3f87638f94c84a13996c074ced58ddab
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

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