4-tert-Butylphenylboronic acid → HCID 59518155, compound

HRID 1160947Notes

Reaction equation

HRID 1160947 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][CH2:5][NH:6][C:7](=[O:29])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([S:19][C:20]2[CH:25]=[C:24]([CH3:26])[C:23](Br)=[C:22]([CH3:28])[CH:21]=2)[CH2:15][CH:16]([CH3:18])[CH3:17])=[CH:10][CH:9]=1.[C:31]([C:35]1[CH:40]=[CH:39][C:38](B(O)O)=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]>>[C:31]([C:35]1[CH:40]=[CH:39][C:38]([C:23]2[C:24]([CH3:26])=[CH:25][C:20]([S:19][CH:14]([C:11]3[CH:10]=[CH:9][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:30])=[O:29])=[CH:13][CH:12]=3)[CH2:15][CH:16]([CH3:17])[CH3:18])=[CH:21][C:22]=2[CH3:28])=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 27343204-tert-Butylphenylboronic acidHCID 67153612HCID 67153612, compound

Product 1

HCID 59518155HCID 59518155, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 358 starting from 3-{4-[1-(4-bromo-3,5-dimethyl-phenylsulfanyl)-3-methyl-butyl]-benzoylamino}-propionic acid methyl ester and 4-tert-butyl phenyl boronic acid. MS: 530.2 [M−H]−.

Sources & evidence

ORD record
ord-bdc62e718a3a4e00aec904e24cc06907
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

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