4-tert-Butylphenylboronic acid → HCID 59518083, compound

HRID 1160951Notes

Reaction equation

HRID 1160951 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][CH2:5][NH:6][C:7](=[O:29])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([O:21][C:22]2[CH:23]=[N:24][C:25](Cl)=[CH:26][CH:27]=2)[CH2:15][CH2:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[CH:10][CH:9]=1.[C:31]([C:35]1[CH:40]=[CH:39][C:38](B(O)O)=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]>>[C:31]([C:35]1[CH:40]=[CH:39][C:38]([C:25]2[N:24]=[CH:23][C:22]([O:21][CH:14]([C:11]3[CH:12]=[CH:13][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:30])=[O:29])=[CH:9][CH:10]=3)[CH2:15][CH2:16][CH2:17][CH:18]([CH3:19])[CH3:20])=[CH:27][CH:26]=2)=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 27343204-tert-Butylphenylboronic acidHCID 86615991HCID 86615991, compound

Product 1

HCID 59518083HCID 59518083, compound

Procedure

The title compounds are prepared in a manner substantially similar to Example 62 starting from 3-{4-[1-(6-chloro-pyridin-3-yloxy)-5-methyl-hexyl]-benzoylamino}-propionic acid methyl ester and 4-tert-butyl phenyl boronic acid. Isomer 1 MS: 515.2 [M−H]−; Isomer 2 MS: 515.2 [M−H]−.

Sources & evidence

ORD record
ord-cccd5c4fdebe4b1c99b336439970d681
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

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