4-tert-Butylphenylboronic acid → HCID 59518078, compound

HRID 1160959Notes

Reaction equation

HRID 1160959 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][CH2:5][NH:6][C:7](=[O:29])[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([O:21][C:22]2[CH:27]=[CH:26][C:25](Br)=[CH:24][CH:23]=2)[CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)=[CH:10][CH:9]=1.[C:31]([C:35]1[CH:40]=[CH:39][C:38](B(O)O)=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]>>[C:31]([C:35]1[CH:40]=[CH:39][C:38]([C:25]2[CH:24]=[CH:23][C:22]([O:21][CH:14]([CH:15]3[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]3)[C:11]3[CH:12]=[CH:13][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:30])=[O:29])=[CH:9][CH:10]=3)=[CH:27][CH:26]=2)=[CH:37][CH:36]=1)([CH3:34])([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 27343204-tert-Butylphenylboronic acidHCID 67153462HCID 67153462, compound

Product 1

HCID 59518078HCID 59518078, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 128 starting from 3-{4-[(4-bromo-phenoxy)-cyclohexyl-methyl]-benzoylamino}-propionic acid methyl ester and 4-tert-butyl phenyl boronic acid. MS: 512.3 [M−H].

Sources & evidence

ORD record
ord-b23f626b6e2441e1b462cbc56ea999cf
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

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