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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1161077Erstellt: 25. Oktober 2026

HCID 57884497, Verbindung → 3-{[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzoic acid

https://huagongshe.com/reaction/1161077

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHCID 57884497HCID 57884497—
Edukt3-{[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzonitrileHCID 66699558—
Produkt3-{[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzoic acidHCID 57884458—

Reaktionsschritte

The title compound is prepared essentially as described for 3-{[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-hydroxy-methyl}-benzoic acid employing 3-{[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-methoxy-methyl}-benzonitrile to give a white solid, 82%. 1H NMR (DMSO-d6) δ 13.00 (bs, 1H), 12.85 (s, 1H), 7.96 (s, 1H), 7.79-7.85 (m, 2H), 7.63 (d, 1H), 7.40-7.48 (m, 5H), 6.72 (d, 1H), 5.50 (s, 1H), 5.24 (s, 2H), 3.30 (s, 3H), 2.58-2.61 (m, 5H), 1.44-1.52 (m, 2H), 0.84-0.88 (m, 3H). LCMS M+1 449.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07816523B2
Quelldatensatzuspto-grants-2010_10
ORD IDord-9796eced84b446a9947cedf9f56c3f03
Quellennotizuspto-grants-2010_10