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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1161141Generated: October 29, 2026

3-[3-(4-Methoxy-phenoxymethyl)-[1,2,4]oxadiazol-5-ylmethyl]-benzoic acid ethyl ester → 3-(3-Hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl ester

https://huagongshe.com/reaction/1161141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(4-Methoxy-phenoxymethyl)-[1,2,4]oxadiazol-5-ylmethyl]-benzoic acid ethyl esterHCID 66699500—
Reactant4-(3-Hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl esterHCID 66699592—
Product3-(3-Hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl esterHCID 66699589—

Reaction Steps

The title compound is prepared essentially as described for 4-(3-hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl ester, employing 3-[3-(4-methoxy-phenoxymethyl)-[1,2,4]oxadiazol-5-ylmethyl]-benzoic acid ethyl ester (81%). LC-MS (m/e): 263 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07816523B2
Source datasetuspto-grants-2010_10
ORD IDord-8b0f1f2cc4cd44faa3a50dc8e853d9d6
Source noteuspto-grants-2010_10