反应详情

To a solution of (S)-2-(5-nitro-1-oxoisoquinolin-2(1H)-yl)propanamide (1.3 g, 0.0050 mol) in methanol (40 mL, 1 mol) and dichloromethane (5 mL) was added palladium on charcoal (0.2 g, 0.001 mol) and stirred under hydrogen (1 atm) for 2 h. The reaction mixture was filtered over celite and the filtrate removed under reduced pressure to yield the pure product as an off white solid. MS m/z=232.5 (M+H).

1. filtrationThe reaction mixture was filtered over celite
2. customthe filtrate removed under reduced pressure
3. customto yield the pure product as an off white solid