HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 59515826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | methyl D-alaninate | HCID 89020 | — |
| Reactant | 5-nitro-1H-isochromen-1-one | HCID 10012760 | — |
| Product | HCID 59515826 | HCID 59515826 | — |
Reaction Steps
5-Nitro-isochromen-1-one (5 g, 0.03 mol) and D-alanine methyl ester (4 g, 0.04 mol) were refluxed in methanol (40 mL, 1 mol) for 2 hours. The volatiles were removed via rotovapor, and the residue was purified via flash column chromatography (330 g of silica gel, 0-50% EtOAc/Hexane) to give a yellow solid. MS m/z 277.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816371B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-5ec8d7c631bf4a9190287c4c31465677 |
| Source note | uspto-grants-2010_10 |