反应详情

A round bottom flask was charged with (R)-6-cyclopropyl-2-(1-hydroxypropan-2-yl)-5-nitroisoquinolin-1(2H)-one (30 mg, 0.0001 mol), acetic anhydride (0.015 mL, 0.00016 mol), pyridine (0.015 mL, 0.00019 mol) and methylene chloride (4 mL, 0.06 mol) and the reaction stirred at room temperature over night. The solvent was then removed and the product was taken to the next step without purification. MS m/z=331.5 (M+H).

1. customThe solvent was then removed
2. customthe product was taken to the next step without purification