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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 116150Generated: November 1, 2026

Trifluoroacetic acid → (+/-)-tert-Butyl 4-((1-(4'-cyano-5-(trifluoromethyl)biphenyl-3-yl)ethoxy)methyl)-4-phenylpiperidine-1-carboxylate

https://huagongshe.com/reaction/116150

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
Reactant4-Cyanophenylboronic acidHCID 2734326—
ReactantTert-butyl 4-[1-[3-bromo-5-(trifluoromethyl)phenyl]ethoxymethyl]-4-phenylpiperidine-1-carboxylateHCID 58993627—
Product(+/-)-tert-Butyl 4-((1-(4'-cyano-5-(trifluoromethyl)biphenyl-3-yl)ethoxy)methyl)-4-phenylpiperidine-1-carboxylateHCID 58993681—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-68128e84088342a282d9416b776cf2b7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)