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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1161690Generated: October 30, 2026

4-Chloro-2,6-diphenylpyrimidine → (2,6-Diphenyl-pyrimidin-4-yl)-(4-trifluoromethoxy-phenyl)-amine

https://huagongshe.com/reaction/1161690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2,6-diphenylpyrimidineHCID 582041—
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
Product(2,6-Diphenyl-pyrimidin-4-yl)-(4-trifluoromethoxy-phenyl)-amineHCID 11575048—

Reaction Steps

The title compound was prepared from 4-chloro-2,6-diphenyl-pyrimidine (0.25 g, 0.93 mmol) and 4-trifluoromethoxy aniline (0.16 g, 0.93 mmol) according to the procedure as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820654B2
Source datasetuspto-grants-2010_10
ORD IDord-71bd11212ccb4d06a1a47cd50e225bc3
Source noteuspto-grants-2010_10