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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1161702Generated: October 29, 2026

4-(Methylthio)aniline → 1-[2-(4-Methylsulfanyl-phenylamino)-6-phenyl-pyrimidin-4-yl]-piperidin-4-ol

https://huagongshe.com/reaction/1161702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylthio)anilineHCID 66038—
Reactant1-(2-Chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-olHCID 58626078—
Product1-[2-(4-Methylsulfanyl-phenylamino)-6-phenyl-pyrimidin-4-yl]-piperidin-4-olHCID 58626109—

Reaction Steps

The title compound was prepared by treating 1-(2-chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-ol (0.3 g, 1.04 mmol) with 4-methylsulfanyl-phenylamine (0.15 g, 1.04 mmol) according to the procedure as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820654B2
Source datasetuspto-grants-2010_10
ORD IDord-aa3479843b7942e7a4fbf702c460fcc8
Source noteuspto-grants-2010_10