Sodium Carbonate → HCID 58626118, compound

Participants

Reaction Steps

The title compound was prepared by reacting (6-chloro-2-phenyl-pyrimidin-4-yl)-(4-methanesulfonyl-phenyl)-amine (0.15 g, 0.41 mmol) with 4-trifluoromethoxy-phenyl boronic acid (0.09 g, 4.3 mmol) in presence of (PPh3)4Pd (0.02 g, 0.017 mmol) and 2 M sodium carbonate (0.35 g in 1.5 mL H2O) in DMF at 80° C. for 12 hours. Followed by work up and column purification to yield the desired compound.

Provenance & Evidence