Sodium Carbonate → HCID 58626111, compound

Participants

Reaction Steps

The title compound was prepared by reacting (4,6-dichloro-pyrimidin-2-yl)-(4-trifluoromethoxy-phenyl)-amine (0.3 g, 0.92 mmol) with 3-methanesulfonyl-phenyl boronic acid (0.37 g, 1.85 mmol) in presence of Pd(OAc)2 (7 mg, 0.02 mmol) and sodium carbonate (0.78 g, 7.4 mmol) in a solvent DMF (10 mL) at 80° C. for 12 hours, followed by work up and column purification.

Provenance & Evidence