Benzoyl Peroxide → HCID 17961860, compound

HRID 1161898Notes

Reaction equation

HRID 1161898 reaction equation
[CH3:1][C:2]([CH3:26])([CH3:25])[C:3]([O:5][C:6]1[C:11](=[O:12])[N:10]([CH3:13])[C:9]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)=[N:8][C:7]=1[C:21]([O:23][CH3:24])=[O:22])=[O:4].[Br:27]N1C(=O)CCC1=O.C(Cl)(Cl)(Cl)Cl.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[Br:27][CH2:20][C:17]1[CH:18]=[CH:19][C:14]([C:9]2[N:10]([CH3:13])[C:11](=[O:12])[C:6]([O:5][C:3](=[O:4])[C:2]([CH3:26])([CH3:25])[CH3:1])=[C:7]([C:21]([O:23][CH3:24])=[O:22])[N:8]=2)=[CH:15][CH:16]=1

Participants

4

Reactant 3

HCID 7187Benzoyl PeroxideHCID 17961704HCID 17961704, compoundHCID 17961771HCID 17961771, compound

Product 1

HCID 17961860HCID 17961860, compound

Procedure

To a vigorously boiling solution of methyl 5-[(2,2-dimethylpropanoyl)oxy]-1-methyl-2-(4-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxylate in carbon tetrachloride N-bromosuccinimide (1 eq.) and benzoyl peroxide (0.05 eq.) were added as dry powders. After 4 hr the mixture was allowed to reach room temperature and the precipitated succinimide was filtered off. The filtrate was evaporated under vacuum and the solid residue was used as such.

Workup

  1. customas dry powders
  2. customto reach room temperature
  3. filtrationthe precipitated succinimide was filtered off
  4. customThe filtrate was evaporated under vacuum

Sources & evidence

ORD record
ord-3499abec17b047e38181d5511b1d38bd
Source dataset
uspto-grants-2010_10
Patent number
US07820660B2

Reaction notes

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